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Commercial Adoption (Small Molecules)

UCL supports towards commercial adoption and NHS uptake of translational small molecules projects.

small molecules roadmap

FDA logo
REVIEW, EVALUATION AND FDA/MHRA APPROVAL:

Once the drugs is effective in clinical trials, the data is gathered and NDA is submitted to the MHRA/FDA for approve the licence of the drug.

听The regulating body will review and evaluate the safety and efficacy from all the data provided. If the benefited of the drug out weights an risk that arise, the drug will be approved.

drug manufacturing
听MANUFACTURING AND POST-RELEASE MONITORING:

The Pharmaceutical company will produce the drug in large quantities and available for patient use. Marketing approval needs to be obtained. The drug is given to the patients and they are monitored to look for any adverse effect that may not have occurred in the clinic trails.

Target
NHS ADOPTION:

Key tips to facilitate adoption -听Continuously undertake internal and external stakeholder review of the small molecules:

  • The Steering Committee should meet regularly (at least every 6 months)
  • Ensure the identification and measurement of tangible data that will support adoption (e.g. outcomes meaningful to ward managers, hospital laboratory managers)

Be mindful of the key 鈥榝acets鈥� developed for successfully adopted:

  • FISCAL OPPORTUNITY:听Clearly defined & attractive market potential
  • SYSTEM OPERATIONS:听Awareness & solutions to operational challenges of delivering the healthcare
  • COMMUNICATION:听Effective publicity of the biologic throughout its lifetime
  • HUMAN FACTORS:听Minimized use-related hazards, risks & inconvenience wherever practically possible
  • PROOF:听Provision of 鈥榳ork as done鈥� evidence (i.e. in both clinical & laboratory scenarios)
  • IPR:听Secure intellectual property rights as early as possible, then drive for market adoption as soon as possible

UCL Support:

鲍颁尝鈥檚听听builds on an increasingly vibrant translational culture across the wider university community by providing integrated support for translational research and industrial partnerships.听

UCL has implemented and is growing strategic platform partnerships to facilitate the accelerated development, commercialisation and adoption of therapeutics into the NHS.

Translation at 皇家华人

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