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ION-DRI Programme

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Translation & Discovery in Action

We hear from the researchersÌýworking to answer fundamental questions about the brain through discovery research and those translating these discoveries into ground-breaking new treatments for patients

Our landmark new facility at Grays Inn RoadÌýwill be home to the UCL Queen Square Institute of Neurology (ION) , the UK Dementia Research Institute (UK DRI) and the UCLH National Hospital for Neurology and Neurosurgery.

Alongside ourÌýfacilities at Queen Square, the new centre willÌýcreate an interdisciplinary, collaborative environment for researchersÌýworking to better understand the diversity and complexity of neurodegenerative diseases like Alzheimer’s through discovery scienceÌýas well asÌýsupporting them to be able toÌýtranslate this knowledge into new diagnostics, treatmentsÌýandÌýtherapies for patients.Ìý

We hear from the researchers and clinicians who are working on some of these ground-breaking new discoveriesÌýand the patients and carers who could benefit from them.Ìý
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Image of COL6A1 staining in spinal cord motor neurons

Translation in Action: Prof Adrian Isaacs

Exploring early changes in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

Mouse spinal cord neuron. Nucleus in blue. Credit NICHDS. Jeong

Translation in Action: Professor Robert Brownstone

Exploring the role of the spinal cord in Tor1a dystonia

A creative workshop for Patterns of Perception in Parkinson’s disease

Translation in Action: Dr Rimona Weil

Exploring fears about dementia in the Parkinson’s community through creative workshops

DNA Double Helix National Institute of Health

Translation in Action: Prof Helene Plun Favreau

Mitochondrial dysfunction, in Parkinson's disease and in other neurodegenerative conditions. 

Alpha synuclein (credit: Shutterstock StudioMolekuul)

Translation in Action: Dr Tim Bartels

 Improving diagnosis of Parkinson’s disease

Fluo Neurons

Translation in Action: Prof Gabriele Lignani

Gene therapy approaches to treat refractory epilepsy

microscopic image of Alzheimer's cell

Discovery in Progress: Dr Soyon Hong

Researching the role of microglia, the primary brain-resident immune cells, in Alzheimer’s disease.