Supporting Earlier-stage Diagnosis

Health economic evaluation of early diagnosis interventions, and modelling of natural history of cancer to support earlier-stage diagnosis.

20 June 2024

Background

Several new diagnostic tests are being developed. Evaluation studies are critical to help assess whether and how new test discoveries can be implemented in practice and offered to patients. Test evaluation requires input from health economics to assess cost-effectiveness, mixed methods research to select the most important evaluation outcomes, and natural history modelling to understand how different cancers progress.

Aims and objectives

To assess the cost-effectiveness of novel diagnostic technology for single or multiple cancers.
To gather evidence from a range of stakeholders to develop a core outcome set to inform future evaluation of novel cancer testing strategies in primary care.
To estimate the impact of delayed diagnosis on stage progression and cancer mortality.

Policy Relevance & Dissemination鈥�

We will produce generalisable evidence to inform the evaluation of new tests. We will support the implementation of emerging tests, and develop a framework for similar evaluations; generate a core outcomes set to guide the evaluation design of future diagnostic technologies; and inform policy on optimal screening and time-to-diagnosis targets needed for maximising reductions in cancer mortality from new tests. 听

The findings will be shared with policymakers in the DHSC, NHS England and cancer charities. They will be published in academic journals and websites/blogs/social media, and presented at conferences.

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