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Selected publications 2024

  • Hendow EK, Iacoviello F, Casajuana ME, Pellet-Many C, Day RM. Hierarchically Structured Biodegradable Microspheres Promote Therapeutic Angiogenesis. Advanced Healthcare Materials. Aug 2024 doi:
  • Bettini A, Camelliti听笔, Stuckey DJ,听Day RM.听Injectable biodegradable microcarriers for iPSC expansion and cardiomyocyte differentiation. Advanced Science. Jul 2024 诲辞颈:听
  • Day RM, Knowles CK. Regenerative treatment may offer a cure for incontinence patients听The Guardian newspaper June 20 2024
  • Ho HMK, Day RM, Craig DQM. An investigation into the effects of processing factors on the properties and scaling-up potential of propranolol-loaded chitosan nanogels. Pharmaceutics. May听2024听诲辞颈:听
  • Bettini A, Patrick PS, Day RM,听Stuckey DJ. 颅颅CT-Visible Microspheres Enable Whole-body In Vivo Tracking of Injectable Tissue Engineering Scaffolds.听Advanced Healthcare Materials. 2024 Apr 28:e2303588.听doi: 10.1002/adhm.202303588
  • Erdogan ZK, Nandin M,听GS Jin,听Yu-Meng L,听Chau D, Day R, Kim H,听Knowles, JC. Lithium-loaded GelMA-PGFs constructs: implications for astrocyte response and regeneration.听Journal of Biomedical Materials Research Part A. 2024 Jul;112(7):1070-1082.听doi: 10.1002/jbm.a.37686

Selected publications 2023

  • Gilbert M, 膶aputov谩 S, Poli D, Kooy M, Sturt G, Parker J, Day RM.听Building rings with spheres: a cell therapy approach to incontinence. BioInsights. 2023听DOI: 10.18609/cgti.2023.167
  • McCord B, Day RM.听Cytotoxic Immune Cells Do Not Affect TDP-43 and p62 Sarcoplasmic Aggregation But Influence TDP-43 Localisation. Scientific Reports. 2023听顿翱滨:听10.1038/蝉41598-023-42824-5听听
  • Cartaxo AL, Fernandes-Platzgummer A, Rodrigues CAV, Melo AM, Tecklenburg K, Margreiter E, Day RM, da Silva CL, Cabral JMS. Developing a Cell-Microcarrier Tissue Engineered Product for Muscle Repair Using a Bioreactor System. Tissue Engineering, Part C. 2023听doi: 10.1089/ten.TEC.2023.0122
  • McCord B, Day RM. Influence of Inflammatory Cytokines IL-1尾 and IFN纬 on Sarcoplasmic Aggregation of p62 and TDP-43 in Myotubes. Mediators of Inflammation 2023听doi: 10.1155/2023/9018470
  • Casajuana ME, Day RM. Production and Utility of Extracellular Vesicles with 3D Culture Methods. Pharmaceutics 2023.听听

Selected publications 2022

  • Desprez C, Danovi D, Knowles CH, Day RM.听Cell Shape Characteristics of Human Skeletal Muscle Cells as a Predictor of Myogenic Competency: A New Paradigm Towards Precision Cell Therapy.听Journal of Tissue Engineering. Nov 2022.听DOI: 10.1177/20417314221139794
  • Ho HMK, Sembi S, Abukhamees S, Day RM, Craig DQM.听An analytical quality by design approach towards a simple and novel HPLC-UV method for quantification of the antifibrotic peptide N-acetyl-seryl-aspartyl-lysyl-proline. Analytical Biochemistry. June 2022.听
  • Ho HMK,听Craig DQM,听Day RM.听Design of Experiment Approach to Modeling the Effects of Formulation and Drug Loading on the Structure and Properties of Therapeutic Nanogels.听Mol Pharm. 2022 Jan 21. doi: 10.1021/acs.molpharmaceut.1c00699.听

Selected publications 2021

  • Hanczar M, Moazen M, Day R. The Significance of Biomechanics and Scaffold Structure for Bladder Tissue Engineering.听Int. J. Mol. Sci. 2021, 22, 12657. DOI:10.3390/ijms222312657
  • Hendow EK, Day RM. A facile approach to therapeutic angiogenesis using a platelet concentrate and microsphere composite. Nanoselect. Nov 2021.听顿翱滨:听
  • Keskin-Erdogan听Z, 听笔atel KD, Chau DYS, Day RM, Kim H-W,听Knowles J.听Utilization of GelMA with Phosphate Glass Fibers for Glial Cell Alignment.听Journal of Biomedical Materials Research: Part A 2021; 109: 2212-2224.听
  • Ho HMK, Craig DQM, Day RM.听Access Routes, Devices and Guidance Methods for Intrapericardial Delivery in Cardiac Conditions.听Trends in Cardiovascular Medicine April 2021.听

Selected publications 2020

  • Paliashvili K, Popov A, Kalber TL, Patrick PS, Hayes A, Henley A, Raynaud FI, Ahmed HU, Day RM.听Peritumoural Delivery of Docetaxel-TIPS Microparticles for Prostate Cancer Adjuvant Therapy.听Advanced听Therapeutics 2020 October听顿翱滨:听10.1002/adtp.202000179
  • Chin MHW,听Norman MDA,Gentleman E, Coppens M-O, Day RM. A Hydrogel-Integrated Culture Device to Interrogate T Cell Activation with Physicochemical Cues. ACS Applied Materials & Interfaces 2020 September听
  • Simitzi C, Vlahovic M, Georgiou A, Keskin-Erdogan Z, Miller J, Day RM. Modular Orthopaedic Tissue Engineering with Implantable Microcarriers and Canine Adipose-Derived Mesenchymal Stromal Cells.听Frontiers in Bioengineering and Biotechnology 2020 July 22; 8(816): 1-15.听
  • Hendow EK, Moazen M, Iacoviello F, Bozec L, Pellet-Many C, Day听听RM.听Microporous Biodegradable Films Promote Therapeutic Angiogenesis. Advanced Healthcare Care Materials. 2020 July 14; 9:1-10.听.听
  • Simitzi C, Hendow E, Li Z, Day RM. Promotion of Proangiogenic Secretome from Mesenchymal Stromal Cells via Hierarchically Structured Biodegradable Microcarriers. Advanced Biosystems听08 June 2020; 4(7): 1-13.听doi.org/10.1002/adbi.202000062
  • Chin MHW, Gentleman E, Coppens MO,听Day RM.听Rethinking Cancer Immunotherapy by Embracing and Engineering Complexity. Trends Biotechnol. 2020 May 25:S0167-7799(20)30124-4. doi: 10.1016/j.tibtech.2020.05.003.
  • Nogueira JCF, Paliashvili K, Bradford A, Di Maggio F, Richards DA,听Day RM, Chudasama V. Functionalised thermally induced phase separation (TIPS) microparticles enabled for "click" chemistry. Org Biomol Chem. 2020 Mar 25;18(12):2215-2218. doi: 10.1039/d0ob00106f.
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Selected publications 2019

  • Paliashvili K, Di Maggio F, Ho HMK, Sathasivam S, Ahmed H, Day RM. A novel adjuvant drug-device combination tissue scaffold for radical prostatectomy. Drug Deliv. 2019 Dec;26(1):1115-1124. doi: 10.1080/10717544.2019.1686085

  • Syed O, Kim JH, Keskin-Erdogan Z, Day RM, El-Fiqi A, Kim HW, Knowles JC. (2019) SIS/aligned fibre scaffold designed to meet layered oesophageal tissue complexity and properties. Acta Biomater. 2019 Aug 22. pii: S1742-7061(19)30562-8. doi: 10.1016/j.actbio.2019.08.015.

Selected publications 2018

  • Culmer, P., Alazmani, A., Bryant, M.,鈥� Day, R.M. (2018) Continence technologies whitepaper: Informing new engineering science research. 2018; Jun 1:954411918784073. doi: 10.1177/0954411918784073

  • Culmer P, Meese H, Day RM (2017) Incontinence: Engineering Innovation to Enhance Quality of Life Institution of Mechanical Engineers Policy Statement. (003).pdf?sfvrsn=2

Selected publications 2017

  • Sofokleous P, Ali S, Wilson P, Buanz A, Gaisford S, Mistry D,听Fellows听A,听Day听RM(2017)Sustained antimicrobial activity and reduced toxicity of oxidative biocides through biodegradable microparticles.听Acta Biomater. 2017; S1742-7061(17)30617-7. doi: 10.1016/j.actbio.2017.10.001听
  • Omolu A, Bailly M, Day RM. (2017) Assessment of solid microneedle rollers to enhance transmembrane delivery of doxycycline and inhibition of MMP activity. Drug Deliv. 24(1):942-951. doi: 10.1080/
  • Liew LJ, Day RM, Dilley RJ. (2017) Tympanic membrane organ culture using cell culture well inserts engrafted with tympanic membrane tissue explants. Biotechniques. 1;62(3):109-114. doi: 10.2144/000114523.
  • Awwad S, Day RM, Khaw PT, Brocchini S, Fadda H. (2017) Sustained release ophthalmic dexamethasone: In vitro in vivo correlations derived from the PK-Eye. Int J Pharm. Feb 20. pii: S0378-5173(17)30137-0. doi: 10.1016/j.ijpharm.2017.02.047.

Selected publications 2016

  • Maini AA, George MJ, Motwani MP, Day RM, Gilroy DW, O'Brien AJ. (2016) A comparison of human neutrophils acquired from four experimental models of inflammation. PLoS ONE. 11 (10), doi:10.1371/journal.pone.0165502
  • Eriksson TM, Day RM, Fedele S, Salih VM. (2016) The regulation of bone turnover in ameloblastoma using an organotypic in vitro co-culture model. J. Tissue Eng. 6: 1-8. DOI: 10.1177/2041731416669629
  • Angelopoulos I, Southern P, Pankhurst QA, Day RM. (2016) Superparamagnetic Iron Oxide Nanoparticles Regulate Smooth Muscle Cell Phenotype. J Biomed Mater Res A. 104(10):2412-9 doi: 10.1002/jbm.a.35780
  • Hendow, E.K., Guhmann P., Wright, B., Sofokleous, P., Parmar, N., Day, R.M. (2016) Biomaterials for hollow organ tissue engineering. Fibrogenesis & Tissue Repair 9:3. doi: 10.1186/s13069-016-0040-6
  • Wright B, Emmanuel A, Athanasakos E, Parmar N, Parker G, Green B, Tailby E, Chandler H, Cushnie J, Pembroke J, Saruchera Y, Vashisht A, Day R. (2016) Women's views on autologous cell-based therapy for post-obstetric incontinence. Regen Med. 11(2):169-80. doi: 10.2217/rme.15.88
  • Malik, S. A., Ng, W. H., Bowen, J., Tang, J., Gomez, A., Kenyon, A. J., & Day, R. M. (2016). Electrospray synthesis and properties of hierarchically structured PLGA TIPS microspheres for use as controlled release technologies. Journal of Colloid and Interface Science, 467, 220-229. doi:10.1016/j.jcis.2016.01.021.

Selected publications 2015

  • Parmar, N., Day, R.M. (2015) TIPS to manipulate myogenesis: retention of myoblast differentiation capacity using microsphere culture. Eur Cell Mater. 30:41-50.听doi: 10.22203/ecm.v030a04
  • Lakhkar, N. J., M Day, R., Kim, H. W., Ludka, K., Mordan, N. J., Salih, V., & Knowles, J. C. (2015). Titanium phosphate glass microcarriers induce enhanced osteogenic cell proliferation and human mesenchymal stem cell protein expression. Journal of tissue engineering, 6, 2041731415617741-?. doi:10.1177/2041731415617741
  • Wright, B., Parmar, N., Bozec, L., Aguayo, S.P., Day, R.M. (2015) A Simple and Robust Method for Pre-wetting Poly (lactic-co-glycolic) Acid Microspheres. Journal of Biomaterials Applications 30(2):147-59. doi: 10.1177/0885328215577297
  • Parmar, N., Ahmadi, R., Day, R.M. A novel method for differentiation of human mesenchymal stem cells into smooth muscle-like cells on clinically deliverable TIPS microparticles. (2015) Tissue Engineering Part C. 21(4):404-12. doi: 10.1089/ten.TEC.2014.0431

Selected publications 2014

  • Fullerton, J.N., Frodsham, G.C.M., Day, R.M. 3D printing: for the many, not the few (2014).听 Nature Biotechnology 32:1086-87. doi:10.1038/nbt.3056
  • Parmar, N., Kumar, L., Emmanuel, A., Day, R. (2014). Regenerative medicine therapies for obstetric trauma-induced fecal incontinence. Regenerative Medicine 9(6), 831-40
  • Syed, O., Walters, N.J., Day, R.M., Hae-Won, K., Knowles, J.C. (2014) Evaluation of decellualrization protocols for production of tubular small intestine submucosa scaffolds for use in oesophageal tissue engineering. Acta Biomaterialia 10(12) 5043-5054. doi: 10.1016/j.actbio.2014.08.024
  • Parmar, N. & Day, R.M. Appropriately sized bioengineered human external anal sphincter constructs (2014).听 Surgery 157(1):177-8. doi: 10.1016/j.surg.2014.05.025
  • Lau, W., Sofokleous, P., Day, R., Stride, E., Edirisinghe, M. A portable device for in situ deposition of bio-products (2014).听 Bioinspired, Biomimetic and Nanobiomaterials. 3(2); 94-105. DOI:10.1680/bbn.13.00030.

    Selected publications 2013

    • Parmar N & Day R. (2013) 'Just can't wait: women's age-related incontinence'听 in 'A Compendium of Essays: Has the Sisterhood forgotten older women?' Eds Sally-Marie Bamford & Jessica Watson; 2013 International Longevity Centre, London, UK.
    • Ghanbar, H., Luo, C., Bakhshi, P., Day, R., Edirisinghe, M. (2013) Preparation of Porous Microsphere-Scaffolds by Electrohydrodynamic Forming and Thermally Induced Phase Separation. Materials Science and Engineering C. 33:2488-98.
    • Riegler, J., Liew, A., Hynes, S., Ortega, D., O'Brien, T., Day, R., Richards, T., Sharif, F., Pankhurst, Q., Lythgoe, M. (2013) Superparamagnetic iron oxide nanoparticle targeting of MSCs in vascular injury. Biomaterials 34(8):1987-94.
    • Abou Neel, E., Bozec, L., Knowles, J. C., Syed, O., Mudera, V., Day, R., Hyun, J. K. (2012). Emerging Collagen Based Therapies Hit the Patient. Advanced Drug Delivery Reviews 65;429-456.
    • Rasekh, M., Ahmad, Z., Frangos, C., Bozec, L., Edirisinghe, M., Day, R. (2013). Spatial and temporal evaluation of cell attachment to printed polycaprolactone microfibres. Acta Biomaterialia 9(2):5052-62.

    Selected publications 2012

    • Gonzalez-Molina, J., Riegler, J., Southern, P., Ortega, D., Frangos, C., Angelopoulos, Y., Husain, S., Lythgoe, M., Pankhurst, Q., Day, R. (2012). Rapid magnetic cell delivery for large tubular bioengineered constructs. Journal of the Royal Society Interface 9(76):3008-16.

    Selected publications 2011

    • Ahmadi, R., Mordan, N., Forbes, A., Day, R. M. (2011). Enhanced attachment, growth and migration of smooth muscle cells on microcarriers produced using thermally induced phase separation. Acta Biomater 7(4), 1542-1549听doi: 10.1016/j.actbio.2010.12.022
    • Rasekh, M., Ahmad, Z., Day, R., Wickham, A., Edirisinghe, M. (2011). Direct Writing of Polycaprolactone Polymer for Potential Biomedical Engineering Applications. Advanced Biomaterials 13(9), B296-B305
    • Day, R. M. (2011). Functional Requirements of Wound Repair Biomaterials. In Farrar, D. (Ed.). Advanced Wound Repair Therapies ( pp.155-169). UK: Woodhead Publishing.

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    Selected publications 2010

    • Foong, K. S., Patel, R., Forbes, A., Day, R. M. (2010). Anti-Tumor Necrosis Factor-Alpha-Loaded Microspheres as a Prospective Novel Treatment for Crohn's Disease Fistulae. Tissue Engineering 16(5):855-64听doi: 10.1089/ten.TEC.2009.0599
    • Keshaw, H., Foong, K. S., Forbes, A., Day, R. M. (2010). Perianal Fistulae in Crohn's Disease: Current and Future Approaches to Treatment. Inflammatory Bowel Diseases 16(5), 870-880.
    • Keshaw, H., Thapar, N., Burns, A. J., Knowles, J., Forbes, A., Day, R. M. (2010). Microporous collagen spheres produced via thermally induced phase separation for tissue regeneration. Acta Biomaterialia 6(3), 1158-1166.
    • Day, R. M. (2010). Alimentary Tract. In Attala, A., Lanza, R., Thomson, J., Nerem, R. (Eds.). Principles of Regenerative Medicine (2nd ed. pp.925-941). London, UK: Academic Press.

    Selected publications 2009

    • Keshaw, H., Georgiou, G., Blaker, J. J., Forbes, A., Knowles, J. C., Day, R. M. (2009). Assessment of Polymer/Bioactive Glass-Composite Microporous Spheres for Tissue Regeneration Applications. Tissue Engineering: Part A 15(7), 1451-1461.听
    • Moosvi, S. R., Day, R. (2009). Bioactive glass modulation of intestinal epithelial cell restitution. Acta Biomaterialia 5(1), 76-83.

    Selected publications 2008

    • Blaker, J. J., Knowles, J. C., Day, R. M. (2008). Novel fabrication techniques to produce microspheres by thermally induced phase separation for tissue engineering and drug delivery. Acta Biomater. 4(2), 264-272.听
    • Blaker, J. J., Pratten, J., Ready, D., Knowles, J. C., Forbes, A., Day, R. M. (2008). Assessment of antimicrobial microspheres as a prospective novel treatment targeted towards the repair of perianal fistulae. Aliment.Pharmacol.Ther. 28(5), 614-622.听